Annual Report (Typeset)
Released
Released
Announcement PDF
Annual
Report
2025
I
2025
Annual
Report
II
LOOKING
TO
THE
FUTUR Strategic Growth,
Driven by Clinical Need
As global incidence of pancreatic cancer continues to rise, our
mission becomes increasingly urgent—and increasingly valuable.
Between 2025 and 2035, new case numbers of pancreatic cancer
are projected to grow significantly across key European markets
such as Germany (+12%), Spain (+19%), and Italy (+15%), while
emerging regions like the Middle East & North Africa (‘MENA’)
area are expected to show an even larger increase of +46%.
These projections guide our expansion strategy: focusing on high-
priority near-term markets while building pathways for long-term
growth in high-potential geographies such as the United States,
China, and Australia.
III
Projected Increase in Pancreatic Cancer Incidence (2025-2035)
Japan
Germany
0 10 20 30 40 50
France
Italy
United
Kingdom
Spain
United
States
Australia
China
MENA
64,265
22,587
9,282
16,1
1
1
1
1,852
16,538
127,748
50,350
4,353
10,762
United States
Germany
Spain
Italy
United Kingdom
France
China
Japan
Australia
MENA
77,446
25,264
1
1,062
18,449
13,934
19,072
170,188
53,129
5,540
15,750
Incidence
(Estimated number of
new cases in 2035)
Incidence
(Estimated number of
new cases in 2025)
Country
Reference: International Agency for Research on Cancer. Cancer Tomorrow [Internet]. Lyon: IARC; 2020 [cited 2025 Jul 24].
Available from: https://gco.iarc.fr/tomorrow
IV
CLINICAL
TRIAL
UPDATE Clinical Advancement
Fueling Strategic
Expansion
TRIPP-FFX Trial Update
TRIPP-FFX, conducted across 15 sites, investigates OncoSil™
in addition to FOLFIRINOX chemotherapy. With recruitment
completed soon after end-FY25, the trial supports potential label
expansion—broadening treatment options and accelerating market
uptake.
These trials underpin our commitment to transforming pancreatic
cancer care and expanding our commercial footprint.
Our ongoing clinical trials are key to expanding OncoSil™’s
potential and accelerating its adoption worldwide.
V
An open-label, multi-centre, randomised
study of TaRgeted Intratumoural Placement
of Phosphorous-32 (OncoSil™) in addition to
FOLFIRINOX chemotherapy versus FOLFIRINOX
chemotherapy alone in patients with unresectable
locally advanced pancreatic adenocarcinoma.
TRIPP-FFX
*in July 2025
Objective
To assess the safety and efficacy of OncoSil™
when given in addition to standard FOLFIRINOX
chemotherapy for treatment of locally
advanced pancreatic cancer.
Primary Endpoint
• Safety and tolerability as determined
by the adverse event profile
• Local disease control rate at 16 weeks
Location and Status
• 15 sites across Spain, UK, Belgium,
Australia and Italy
• Recruitment completed*
Commercial Impact
Accelerates market penetration with label
expansion to include use of OncoSil™ device
in addition to FOLFIRINOX chemotherapy
VI
CLINICAL
TRIAL
UPDATE Clinical Advancement
Fueling Strategic
Expansion
PANCOSIL (Investigator-Initiated Study)
Trial Update
PANCOSIL, initiated by Amsterdam UMC, explores a novel
delivery method via Interventional Radiology—introducing
OncoSil™ to a new medical specialty. With recruitment completed
soon after end-FY25, this trial aims to lower adoption barriers and
drive faster market entry.
VII
Safety and feasibility of CT-guided percutaneous
radionuclide therapy (RNT) with the OncoSil™ device in
patients with non-progressive locally advanced pancreatic
cancer (PANCOSIL): an open-label, single-arm phase
1-2 feasibility study.
PANCOSIL
(Investigator-Initiated Study)
*in July 2025
Objective
To assess the safety and feasibility of
percutaneous CT or ultrasound-guided RNT using
the OncoSil™ device in patients with
non-progressive locally advanced pancreatic
cancer after induction chemotherapy treatment.
Primary Endpoint
Safety and feasibility of percutaneous RNT using
the OncoSil™ device defined by the percentage
of device- or procedure-related adverse events
(> grade 3) until 90 days post-procedure.
Location and Status
• Amsterdam UMC, The Netherlands
• Recruitment completed*
Commercial Impact
Accelerates market penetration with lower
barriers to adoption via a new method of
delivery for a new medical speciality
(Interventional Radiology)
VIII
SITE
TRAINING
UPDAT Empowering Clinical
Readiness Across
Regions
As OncoSil™ continues to expand across new territories, structured
site training is essential to ensure clinical excellence and consistent
treatment delivery. Over the past year, we have made significant
progress, with training programs launched or completed in key
markets including Spain, Italy, Turkey and Germany.
Several countries now have fully trained and ready-to-activate
sites, while others have already begun treating patients with
OncoSil™. This growing network of trained centres not only
demonstrates increasing adoption in clinical settings, but also
accelerates our path to broader commercial availability.
IX
Türkiye
Italy
Germany
Belgium
Israel
Austria
Greece
Netherlands
Spain
Portugual
United Kingdom
2 3 3
5 4
2 3
2
10 13
1
1 2 15
11
1
4 3
1
Training Commenced
Training Completed
and ready to start
Sites using OncoSil™
X
FY25
HIGHLIGHT A Year of Momentum
and Milestones
FY25 marked a period of exceptional progress and validation for
OncoSil Medical. From significant regulatory approvals across
Europe to pivotal clinical trial recruitment milestones, the year was
defined by acceleration on every front.
Key comparative analysis further reinforced the clinical value of
OncoSil™ in the treatment of pancreatic cancer, highlighting its
superiority over conventional therapies. At the same time, OncoSil
Medical expanded its global footprint through new distribution
agreements and successfully raised capital to fuel continued growth.
These achievements collectively strengthen OncoSil Medical’s
position as an innovative leader in interventional oncology.
January 2025:
Lel Smits appointed
as Non-Executive
Director
XI
September 2024:
First Comparative Analysis
Indicates Significant Benefits from
Adding OncoSil™ to Chemotherapy
for Pancreatic Cancer
May 2025:
Comparative Analysis Reports
Superiority of OncoSil™ Over
Stereotactic Body Radiation Therapy
in Patients with Pancreatic Cancer
January 2025:
MDR Approval
Received from BSI
November 2024:
OncoSil Medical Signs
Distribution Agreements for
Nordics and Egypt
October 2024:
Distribution
Agreement signed
for the GCC Region
October 2024:
UKCA Renewal Certificates
Without Post-Market
Restrictions received
October 2024:
G-BA Approval
Received for OncoSil™
Device in Germany
October 2024:
OncoSil Medical
successfully completes
a $7 million Placement
June 2025:
99% recruitment achieved
in TRIPP-FFX trial,
95% recruitment achieved
in PANCOSIL study.*
May 2025:
OncoSil Medical announces
$8.7m Capital Raise, completed
over June and July 2025
XII
*Recruitment for both studies have completed in July 2025.
PATIENT
&
PHYSICIAN
INTERVIEW
Voices from the
Frontline of Care
At the heart of OncoSil Medical’s mission are the patients we
serve and the dedicated physicians who guide their journey. In this
section, we present first-hand perspectives from both physicians
and patients—stories that illuminate resilience, renewed hope, and
the meaningful clinical impact of this innovative treatment.These
perspectives offer a powerful glimpse into the real-world difference
OncoSil Medical is making in the fight against pancreatic cancer,
reflecting the profound human and medical significance behind
every case.
XIII
Patient Story:
Antonia Pineiro
Finding Strength, Hope, and
Healing Through OncoSil™
Having the opportunity to have
all this treatment made me
hopeful and proud that all of
this happened to me.
Antonia Pineiro’s journey with pancreatic cancer is one marked
by resilience, courage, and optimism. When offered OncoSil™
treatment, she embraced it with optimism. “I felt happy because I
hoped that this treatment would help improve my situation going
forward,” she recalls.
Despite the challenges of chemotherapy, Antonia experienced
no noticeable side effects from OncoSil™ and gradually returned
to everyday activities. More than her own recovery, she focused
on supporting her family: “It affected my family a lot, especially
my daughter. I had to support them. Because if I collapse, they
collapse. So we had to keep moving forward together.”
Today, Antonia feels stronger and encourages others to consider
this treatment.
It affected my family a lot, especially my daughter.
I had to support them. Because if I collapse, they collapse.
So we had to keep moving forward together.
XIV
PATIENT
&
PHYSICIAN
INTERVIEW
Dr. José Lariño Noia
Department of
Gastroenterology at the
University Hospital of
Santiago de Compostela
Dr. José Lariño Noia, who has extensive
experience in managing pancreatic cancer
patients, emphasizes the urgency and severity of
the disease, and the profound impact that
innovative treatments like OncoSil™ can have on
both patients and care teams.
He highlights the therapy’s potential not only to
improve survival outcomes but also to convert
previously inoperable tumors into surgical
candidates. Most importantly, he underscores the
value of offering patients a tangible path forward
in the face of a difficult diagnosis.
Pancreatic cancer is devastating.
Anything that offers hope that can improve survival and
make a tumour operable is a significant advance.
What truly excites me about the
OncoSil™ procedure is that we’re
not just delivering treatment, we’re
giving patients real hope, and the
possibility of a better outcome.
Their gratitude is priceless.
XV
Dr. Virginia Pubul Núñez
Nuclear Medicine physician and
Head of the Nuclear Medicine
Department at the University
Hospital of Santiago de Compostela
OncoSil™ treatment is a fantastic
new opportunity for pancreatic
cancer patients who have very
few treatment options.
Dr. Virginia Pubul Núñez plays a central role in the multidisciplinary
process of administering OncoSil™ treatment for patients with
pancreatic cancer.
Each patient is carefully reviewed by a multidisciplinary committee
of specialists from Medical Oncology, Gastroenterology, Surgery,
and Nuclear Medicine to determine suitability. Following the
committee’s decision, Dr. Pubul Núñez and her team guide patients
through the procedure, from diagnostic imaging and tumor sizing
to the intratumoral implantation of the OncoSil™ device under
endoscopic ultrasound guidance.
Post-procedure, a SPECT-CT scan is performed to confirm
accurate placement by detecting the Bremstrahlung radiation from
Phosphorus-32.
This is a highly coordinated, multidisciplinary procedure that allows us
to personalise care with precision. We see promising results in terms of
local tumor control and quality of life, which gives our patients a real
reason to hope.
XVI
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Corporate directory
Chair’s letter
CEO’s report
Directors’ report
Auditor’s independence declaration
Statement of profit or loss and other comprehensive income
Statement of financial position
Statement of changes in equity
Statement of cash flows
Notes to the financial statements
Consolidated entity disclosure statement
Directors’ declaration
Independent auditor’s report to the members of OncoSil Medical Ltd
Shareholder information
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28
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56
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61
CONTENTS
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Directors Mr Douglas Cubbin - Chairman
Mr Nigel Lange
Ms Lel Smits
Dr Thomas Duthy
Company secretary Ms Olga Smejkalova
Notice of annual general meeting The details of the annual general meeting of OncoSil Medical Ltd are:
1
1:00 am (AEDT)
Wednesday 19 November 2025
The offices of K & L Gates, Level 25, 525 Collins Street, Melbourne, Victoria
Registered office Level 3
62 Lygon Street
Carlton South, Victoria 3053
Phone: +61 2 8935 9629
Principal place of business Level 5
7 Eden Park Drive
Macquarie Park, NSW 21
13
Phone: +61 2 8935 9629
Share register Boardroom Pty Limited
Level 8
210 George Street
Sydney NSW 2000
Phone: +61 2 9290 9600
Auditor Crowe Sydney
Level 24
1 O’Connell Street
Sydney NSW 2000
Solicitors K&L Gates
Level 25, South Tower
525 Collins Street
Melbourne VIC 3000
Bankers National Australia Bank
330 Collins Street
Melbourne VIC 3000
Stock exchange listing OncoSil Medical Ltd shares are listed on the Australian Securities
Exchange (ASX code: OSL)
Website www.oncosil.com
Corporate Governance Statement OncoSil Medical Ltd and the Board of Directors are committed to
achieving and demonstrating the highest standards of corporate governance.
OncoSil Medical Ltd has reviewed its corporate governance practices against
the Corporate Governance Principles and Recommendations (4th Edition)
published by the ASX Corporate Governance Council.
Details of the corporate governance report is available on the Group website at:
https://www.oncosil.com/investors
3
DIRECTORS’
REPORT
ONCOSIL MEDICAL LTD 30 JUNE 2025
CHAIR’S LETTER
restrictions, significantly simplifying commercial treatment initiation
in the EU and UK, accelerating our market access capabilities and
shortening sales cycles.
Clinical and Commercial Expansion
Our global footprint continues to strengthen. Notably:
• The PANCOSIL and TRIPP-FFX clinical trials achieved 95% and
99% recruitment respectively by the end of June 2025. Both
trials went on to complete recruitment in July 2025.
• Our OncoSil™ device has been deployed in more than 30
treatments in Spain.
• We signed distribution agreements serving Egypt, the Gulf
Cooperation Council (GCC) countries (which includes the
United Arab Emirates (UAE), Qatar, Oman, and Bahrain),
and the Nordic countries (Sweden, Denmark, Norway, and
Finland), expanding our market reach.
• During the third quarter of FY2025, OncoSil Medical received
a $1,050,896 R&D tax incentive, bolstering our capital for
continued innovation in targeted radiotherapy.
• Furthermore, at Digestive Disease Week 2025 (3 – 6 May
2025, San Diego), investigators from the Royal Adelaide
Hospital presented a comparative study demonstrating
superior outcomes of OncoSil™ over SBRT (stereotactic body
radiation therapy) in patients with locally advanced pancreatic
cancer – improved median overall survival (22 months vs. 14
months), extended progression-free survival, and a favourable
safety profile.
Capital Consolidation
In June 2025, shareholders approved – and we completed –
a 1-for-400 consolidation of the Company’s issued capital.
Douglas Cubbin
Non-executive Chairman
OncoSil Medical
Dear Shareholders,
I am pleased to present OncoSil Medical’s Annual
Report for the fiscal year ended 30 June 2025.
This period has been transformational for our
company, marked by strong operational progress
and significant corporate developments.
Regulatory and Market Access
Achievements
In late January 2025, we secured Medical
Device Regulation (MDR) certification for the
OncoSil™ device from BSI, the EU Notified Body.
This pivotal approval removes prior post-market
4
This has streamlined our capital structure and positioned
us for stronger market engagement and investor clarity.
Australian institution invested $2.7
million through placement
As announced on 25 July 2024, OncoSil completed
a placement with Pengana Capital Group for $2.7
million before costs via the issue of approximately
(on a pre-capital consolidation basis) 386 million
new fully paid ordinary shares in the Company (New
Shares) at $0.007 per New Share (Offer Price)
together with one OSLOB Short Dated Listed Option
(expiry date 30 June 2025, exercise price $0.009
each) (New Options) for each New Share issued
under the Placement.
Robust Capital Raises
We completed a $8.0 million capital raise through
a placement of $7.0 million in November 2024 and
a $1 million Share Purchase Plan (SPP) in December
2024. The funds were applied to further investment
in OncoSil’s Macquarie Park manufacturing facility,
funding of clinical trials, and other working capital
costs and costs of the offer.
We successfully executed an $8.7 million capital
raise, comprising a $6.7 million placement and a $2
million SPP. Tranche 1 of the placement ($3.2 million)
completed in June 2025 and Tranche 2 of the placement
($3.5 million) and the $2 million SPP completed in July
2025. The raise was backed by both new and existing
institutional investors, with Pengana Capital Group
playing a cornerstone role. These funds raised will
primarily support the commercialisation of our OncoSil™
device across Europe and our existing territories.
Governance and Board Strengthening
In January 2025, we welcomed Ms. Lel Smits to
the Board as a Non-Executive Director. With deep
expertise in n corporate communications, governance,
and strategic engagement from advising over 500
ASX listed entities, Ms Smits strengthens our leadership
team as we scale our operations.
Shortly after the end of the financial year, on 1
1 July
2025 we announced the appointment of Dr Thomas
Duthy as a Non-Executive Director. He brings more
than 21 years of experience across financial markets,
corporate development, and board-level roles in the
healthcare and life sciences sectors. Dr Duthy is the
Founder and Director of Nemean Group, a corporate
advisory firm serving healthcare and technology
companies, has been involved in numerous successful
M&A transactions and holds relevant experience in
the oncology device setting, given his previous role
as Head of Corporate Development and Investor
Relations at Sirtex Medical (ASX:SRX), where he
played a key role in its $1.9 billion acquisition.
In conjunction with Dr Duthy’s appointment, Dr
Gabriel Liberatore resigned from the OncoSil Board of
Directors for personal reasons, effective 1
1 July 2025.
The Board extends its sincere thanks to Dr Liberatore
for his valuable contribution and dedicated service to
OncoSil Medical.
Looking Ahead
As we move into FY26, OncoSil is well-positioned
to deliver on its mission. We remain focussed on
expanding commercial adoption of our device,
completing our key clinical trials, and pursuing new
market opportunities. With a strengthened capital
position and a dedicated team, we are confident in
our ability to build on the foundation laid this year.
To our shareholders, thank you for your continued
support and belief in our vision. Together, we
are progressing toward a future where OncoSil™
becomes a meaningful part of the global fight against
pancreatic cancer.
Douglas Cubbin
Non-executive Chairman
OncoSil Medical
5
DIRECTORS’
REPORT
ONCOSIL MEDICAL LTD 30 JUNE 2025
CEO’S REPORT
A key highlight of the year was the approval from German Federal
Joint Committee (Gemeinsamer Bundesausschuss, G-BA) for
the clinical trial in Germany. This is one of the most significant
achievements in OncoSil’s history. The G-BA is Germany’s highest
decision-making body for healthcare reimbursement, and this
approval and successful completion of the clinical trial will broaden
access to the OncoSil™ device across the German public hospital
system. A successful completion of the clinical trial paves the way
for further reimbursement negotiations in other EU member states
and beyond, as the G-BA decision is often referenced by peer
health systems. It also validates the clinical strength of our data and
positions the OncoSil™ device as a credible and scalable cancer
therapy option in one of the world’s most advanced healthcare
environments.
In parallel, we have seen a sharp increase in German
hospital applications for NUB (Neue Untersuchungs- und
Behandlungsmethoden) approvals, which rose by over 40%
year-on-year. NUB is a hospital-led process to secure temporary,
hospital-specific extra reimbursement for new inpatient treatments.
This approval serves to unlock access to funding in Europe’s largest
market.
Another major regulatory milestone was achieving certification
under the EU MDR framework. The MDR represents one of the most
stringent and comprehensive medical device regulatory regimes
globally. Achieving certification under this standard is a rigorous
process that speaks to the safety, quality, and clinical robustness
of our product. Importantly, MDR approval ensures our continued
access to EU markets beyond the legacy MDD (Medical Device
Directive) certification and removes previous restrictions on post-
Mr Nigel Lange
Chief Executive Officer &
Managing Director
OncoSil Medical
Dear Shareholders,
I am pleased to present OncoSil Medical Ltd’s
CEO Report for the financial year ended 30 June
2025—a year in which we delivered meaningful
progress toward our mission of improving
outcomes for patients with pancreatic cancer. This
year was defined by strong clinical momentum,
an exceptional regulatory breakthrough in
Germany, and the continued commercialisation
of our innovative brachytherapy device across
key global markets.
6
market commercialisation. This certification reinforces
OncoSil’s position as a trusted device manufacturer
and provides a strong foundation for long-term growth
across Europe and the UK.
In parallel, we have made substantial progress in our
clinical development program. Recruitment in both our
TRIPP FFX and PANCOSIL studies surpassed the >90%
recruitment at the end of FY25 (both studies were
completed in July 2025), a significant achievement
that reflects strong clinical interest and institutional
confidence in our therapy. These trials are essential
to our long-term strategy. TRIPP-FFX study is designed
to generate high-quality evidence on the efficacy
and safety of OncoSil™ when used in combination
with standard-of-care chemotherapy (FOLFIRINOX).
PANCOSIL study evaluates the safety and feasibility of
CT-guided percutaneous implantation of OncoSilTM
device. The data from these studies will not only
support further regulatory engagement with additions
to our existing labelling but also strengthen our case
for reimbursement and clinical expansion in new and
existing markets.
From a commercial perspective, FY25 marked our
strongest sales performance to date. Dose sales
increased by 100% year-on-year, contributing
to an 83% increase in full-year sales and a 127%
uplift in revenue compared to the prior year. Pricing
has remained consistent throughout the year.
Approximately 60% of revenue was generated by
direct sales while the remaining 40% was distributor
generated. These results were driven by growing
demand across the Europe, particularly in Spain,
Greece and Israel, reflecting both the maturing of our
commercial model and the accelerating recognition
of our technology in clinical practice. We also
broadenedourgeographicreach,securingdistribution
agreements across the Nordic region, Egypt, and the
Gulf countries ensuring that more patients worldwide
will have access to our device.
To support these growth initiatives, we took proactive
steps to strengthen our balance sheet. Over the course
of the year, we completed capital raises totalling more
than $14 million, including a successful institutional
placement and share purchase plans. These funds
have extended our operational runway into FY26 and
will enable us to continue investing in clinical trials,
market development, and regulatory engagement.
We also received a $1.05 million R&D tax refund,
which reflects our continued commitment to innovation
and evidence-based medicine.
In support of our longer-term manufacturing and
operational strategy, we also made important
progress on the development of our Macquarie Park
manufacturing facility in Sydney. The facility is being
prepared as a dedicated site to produce the OncoSil™
device and is designed to meet the rigorous quality
standards required for global regulatory approvals.
Once operational, the Macquarie Park facility
will enhance our control over production, improve
scalability, and support the transition toward in-house
manufacturing, thereby strengthening supply chain
security and cost efficiency over time.
As we look ahead to FY26, our priorities are clear. We
will continue driving adoption in key existing markets,
launch in new countries, and place a strong emphasis
on accelerating sales growth and maximising revenue.
With the major regulatory barriers now behind us and
growing clinical endorsement ahead of us, we believe
we are at a genuine inflection point in our journey.
In closing, I would like to thank our shareholders for
your ongoing support and trust. The progress we have
made over the past year reflects the resilience and
dedication of our team, the strength of our technology,
and the clarity of our mission. We remain committed
to improving the lives of patients living with pancreatic
cancer and to delivering long-term, sustainable value
to you—our shareholders.
Nigel Lange
Chief Executive Officer & Managing Director
OncoSil Medical
7
DIRECTORS’
REPORT
ONCOSIL MEDICAL LTD 30 JUNE 2025
The directors present their report, together with the financial statements, on the consolidated entity (referred to hereafter as the ‘Group’)
consisting of OncoSil Medical Ltd (referred to hereafter as the ‘Company’ or ‘parent entity’) and the entities it controlled at the end of, or
during, the year ended 30 June 2025.
Directors
The following persons were directors of OncoSil Medical Ltd during the whole of the financial year and up to the date of this report, unless
otherwise stated:
Mr Douglas Cubbin Independent Non-Executive Chairman
Mr Nigel Lange Chief Executive Officer and Managing Director
Ms Lel Smits Independent Non-Executive Director (appointed 15 January 2025)
Dr Thomas Duthy Independent Non-Executive Director (appointed on 1
1 July 2025)
Dr Gabriel Liberatore Independent Non-Executive Director (resigned on 1
1 July 2025)
Information on directors
Name MR DOUGLAS CUBBIN
Title Non-Executive Director and Chairman
Qualifications BBus., FCPA, GAICD
Experience and expertise Mr Cubbin is an experienced biopharmaceutical executive with over 31 years’ experience in senior executive,
CFO, Director and Chair roles, across varied industries. During his tenure as Group Chief Financial Officer at
Telix Pharmaceuticals Limited (ASX:TLX), a global biopharmaceutical company focused on the development and
commercialisation of diagnostic and therapeutic radiopharmaceuticals, he was a key member of the team which
successfully completed the IPO, raised $270 million in capital and grew the business to a multi-billion dollar market
capitalisation. Mr Cubbin has also served as Chairman of various boards, including Australian Nuclear Science and
Technology Organisation (ANSTO) Nuclear Medicine.
Other current directorships None
Former directorships (last 3 years) None
Special responsibilities Member of the Nomination and Remuneration Committee and member of Audit and Risk Committee
Interests in shares 62,000 ordinary shares (Owned by related party)
Interests in options 12,500 options
18,750 listed options (Owned by related party)
25,000 unlisted options (Owned by related party)
Name MR NIGEL LANGE
Title Chief Executive Officer and Managing Director
Qualifications BA, B.Comm
Experience and expertise Nigel joined the Company in May 2020 as Europe, Middle East and Africa (‘EMEA’) President and brings with him over 31
years of experience in the medical devices industry. Since 2003, Nigel has held various leadership roles with Sirtex Medical,
a global leader in brachytherapy treatment for liver cancer. From 2003, Nigel served as Chief Executive Officer of Sirtex’s
European business, responsible for establishing their brachytherapy device in over 300 centres across Europe and the Middle
East. Since 2017, Nigel served as Group Chief Commercial Officer where he was responsible for all commercial aspects of
the global business. During this time, Nigel has also held interim roles including Interim Group CEO and Interim CEO of Asia
Pacific.
Other current directorships None
Former directorships (last 3 years) None
Special responsibilities Member of the Nomination and Remuneration Committee and member of Audit and Risk Committee
Interests in shares
3,750 ordinary shares
14,296 performance dependent loan shares
Interests in options 2,500 listed options
Interests in rights 242,030 performance rights
8
Name MS LEL SMITS
Title Non-Executive Director (appointed on 15 January 2025)
Qualifications
Graduate of Australian Institute of Company Directors’ (AICD) Company Directors Course, has secured a Diploma of
Investor Relations from Australasian Investor Relations Association (AIRA) and a Master of Arts in Journalism from University
of Technology, Sydney (UTS).
Experience and expertise Lel Smits is an award-winning entrepreneur, director and leader with a significant track record advising more than 500
ASX-listed management teams and Boards and serving as a Director on Australian Shareholders’ Association since 2021.
Lel was awarded Director of the Year by Women in Finance in 2024 and 2022 and Communications and Marketing
Professional of the Year by Women in Wealth in 2025. Commencing her career as a journalist, Lel gained extensive global
financial markets experience through producing and presenting thousands of finance reports and CEO interviews as a
broadcast finance journalist in Australia and as a New York foreign correspondent for the Australian Financial Review,
reporting from Wall Street, U.S.A. Extensive ASX listed company experience and formal education foundations propelled
Lel to advise and contribute to more entrepreneurial ventures and boards through governance, strategy and risk oversight
and marketing, brand, communications and corporate affairs. Lel is currently a Director of Australian Shareholders’
Association.
Other current directorships None
Former directorships (last 3 years) None
Special responsibilities Member of Audit and Risk Committee.
Interests in shares None
Interests in options 7,500 options
Name DR THOMAS DUTHY
Title Non-Executive Director (appointed on 1
1 July 2025)
Qualifications Dr Duthy holds a PhD from the University of Adelaide and an MBA from Deakin University.
E
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